Summary: This paper focuses on the disparities that persist in India’s health sector across different states. Following the conventional measures of regional inequality such as standard deviation and coefficient of variation, we investigate the spatial variations across the Indian states in terms of three basic health indicators viz. infant mortality rate (IMR), under five mortality and maternal mortality rates. We analyzed the temporal variations of regional disparities of IMR for the period 1998 to 2012. A multiple cross regression of IMR on medical and non-medical conditions show the role of socio-economic and the health infrastructure as significant in determining health outcomes.