In these articles analyzing problems and perspectives in countering religious militants groups in Afghanistan and their scenarios. The mostly regional organizations have different approaches in countering common threats from the militants groups. In global levels exists strong confrontations with Euro-Atlantic and Eurasian regional security organisations as NATO, OSCE, CSTO and SCO in countering security and terrorism issues and targeting information’s. The limited transnational military cooperation rendering ineffectual any efforts to pursue fleeing insurgents, or contains the conflict. Therefore only through joint efforts of the regions will be preventing expanded threats from the Afghanistan to neighbor regions and beyond.