연구정보
An assessment of adverse drug reactions among HIV positive patients receiving antiretroviral treatment in South Africa
남아프리카공화국 국외연구자료 기타 Lieketseng J Masenyetse, Samuel OM Manda and Henry G Mwambi AIDS 발간일 : 2015-03-05 등록일 : 2015-03-06 원문링크
Abstract
Antiretroviral treatment (ART) has been effective in reducing HIV/AIDS related morbidity and mortality. However, the use and uptake of ART has resulted in adverse reactions, due mainly to the medicine’s toxicity and interactions with other medicines. The timing of adverse drug reactions (ADRs) among these patients is a critical public health issue for antiretroviral (ARV) treatment adherence and retention. Reliable monitoring of HIV patients on ART is through a structured pharmacovigilance surveillance system. However, recurrent nature of these data pose challenges in their analyses. This study aimed at modelling the timing of ADR events in HIV patients on ART using correlated time-to-event models.